Artemisia afra, luteolin, virus

Several authors have documented the efficacy of luteolin against pulmonary diseases. The highest concentration of luteolin is found in Artemisia afra at 1.9 mg/g. A. Dube, Thesis, Artemisia afra, University Western Cape, 2006. Mucus overproductionis one of the most important pathological features of chronic inflammatory airway diseases that contribute to morbidity and mortality. It reduces ciliar motility, damages local defensive functions and promotes bacterial colonization. As a natural flavonoid luteolin has multiple biological activities, such as anti-inflammatory and anti-oxidant properties. A Chinese study found that the administration of luteolin effectively attenuates mucus overproduction. Mei-Li Shen, Chen-Hung, Luteolin attenuates airway mucus overproduction. Scientific Reports, 2016, 6 : 32576 Kuo My, Liao MF, Luteolin attenuates the pulmonary inflammatory response. Food and Chemical Toxicology, 2011, 49(10) : 2660-6 M. Das, A Ram, Luteolin alleviates Bronchonstriction and Airway Hyperreactivity, Inflamm Res, 2003, 52,(3): 101-6