Beta-hematin inhibition and antimalarial properties Recent results obtained at the AlQuds University in partnership with IFBV-BELHERB from Luxembourg show that freshly prepared infusion of Artemisia annua or Artemisia afra is stronger than chloroquine in the inhibition of beta-hematin (hemozoin) formation. In infected erythrocytes, the malaria parasite generates large quantities of toxic ferri-heme, the Achille’s heel of Plasmodium. With hydrogen peroxyde which is present in all living beings, heme forms aggressive radicals which kill...

Beta-hematin inhibition and antimalarial properties Recent results obtained at the AlQuds University in partnership with IFBV-BELHERB from Luxembourg show that freshly prepared infusion of Artemisia annua or Artemisia afra is stronger than chloroquine in the inhibition of beta-hematin (hemozoin) formation. In infected erythrocytes, the malaria parasite generates large quantities of toxic ferri-heme, the Achille’s heel of Plasmodium. With hydrogen peroxyde which is present in all living beings, heme forms aggressive radicals which kill...

200 years ago, in 1830 the anthelmintic properties of santonin were discovered, simultaneously by Dr Kahler in Düsseldorf and Dr Alms in Mecklenburg in a plant from Turkestan, Artemisia cina. Its presence, although at lower concentrations, was later found in Artemisia maritima, Artemisia gallica, Artemisia absinthium, Artemisia campestris, Artemisia sieberi. Non declared author, Berichte der Deutschen Chemischen Gesellschaft , 1867, Vol 6, 875-167 Stanislao Cannizzaro is known widely for his document on santonin which he presented at...

The apicoplast is a plastid organelle, homologous to chloroplasts of plants or algae, that is found in apicomplexan parasites like Plasmodium or Toxoplasma. In hinsight it seems incredible that such an organelle could so long have concealed its identity in parasites that have received as much scientific attention as Plasmodium Chakraborty Arnish, Understanding the biology of the Plasmodium falciparum apicoplast; an excellent target for antimalarial drug development, Life Sciences (2016), doi: 10.1016/j.lfs.2016.06.030) Apicoplast...

Artemisia afra a potential flagship for African medicinal plants This plant is growing from the Cape to Addis Abeba, from Mombasa to Kinshasa, wating to ber harvested, registered by the Ministry of Health in Tanzania, listed in the Pharmacopeia of South Africa, Ethiopia, Kenya, Zambia, Zimbabwe, Angola, RDCongo and/or in several research papers of this African region. Its use in these countries was documented for the first time in1962 Watt JM, Breyer-Brandwijk MG, (1962). The Medicinal and Poisonous Plants of Southern and Eastern...